Senior Scientist II, Biologics Purification
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.
Job Description
Join AbbVies Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.). Key Responsibilities: - Lead the purification of bispecific biologics to support critical research assays and studies
- Design and execution of robust process development strategies necessary to address production liabilities which factor into future process scalability.
- Apply advanced bioprocessing and chromatography techniques at large scale
- Utilize in silico tools, DOE methodologies, and predictive modeling to optimize protein separation and maximize yield/quality
- Integrate and manage analytical data using LIMS, ETL tools, and data extraction APIs
- Collaborate with multidisciplinary teams, translating molecular insights into functional results
- Stay current with emerging scientific literature to foster innovation and continuous improvement
- Present findings clearly to diverse audiences and document results with rigor
Qualifications
- BS, MS, or PhD in Bioinformatics, Biophysics, Chemical Engineering, or related field with typically 12+ years (BS), 10+ years (MS), or 4+ years (PhD) of experience
- Deep proficiency in large-scale bioprocessing and chromatography
- Skilled in software systems and/or programming languages: Unicorn, Chromeleon, Empower, JMP, Minitab, Python, SDMS platforms
- Experience with in silico tools/models and DOE to both predict and optimize protein separation behavior based upon critical process parameters.
- Experience with data extraction API, ETL tools and LIMS platforms for data acquisition, integration, and management across multiple analytical platforms is a plus
- Strong understanding of molecular and post-translational attributes of biologics
- Exceptional analytical, communication, and presentation skills
- Collaborative spirit and dedication to scientific excellence
Why AbbVie? Here, we combine advanced science with our strong values, cultivating a culture where curiosity is encouraged and meaningful contributions are recognized. Grow your career, innovate boldly, and make a difference in the lives of patients around the globe. Ready to pioneer the future of biologics? Apply and transform science into health at AbbVie.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
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